USP16 antibody (Center)

Catalog No. ABIN2796351

This anti-USP16 antibody is a Rabbit Polyclonal antibody detecting USP16 in WB. Suitable for Human.

Quick Overview for USP16 antibody (Center) (ABIN2796351)

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP16 Antibody

Binding Specificity: AA 386-416, Center

Purpose: Rabbit Anti-Human USP16 (Center) Antibody

Immunogen: This USP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-416 amino acids from the Central region of human USP16.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-USP16 Pab was detected using the purified Pab.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for USP16

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Alternative Name: USP16

Background:

Target Description: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Gene Symbol: USP16

Molecular Weight: 93570 Da

Gene ID: 10600

UniProt: Q9Y5T5